Combined immunodeficiency in 3 foals

Severe combined immunodeficiency presented with septic arthritis: A case report

Severe combined immunodeficiency is a rare, fatal syndrome of diverse genetic cause in which there is combined absence of T-lymphocyte and B-lymphocyte function (and in many cases also natural killer, or NK lymphocyte function). These defects lead to extreme susceptibility to serious infections. Without intervention, the T and B-cell dysfunction usually results in severe infection and death in ...

A case of severe combined immunodeficiency presenting with CMV pneumonia

A five month-old girl was admitted in Ali Asghar Children’s Hospital with a history of three months of fever, cough and dyspnea that her symptoms have exacerbated since two weeks before admission. She was the first child of the family born to consanguineous parents. She was clinically healthy in the past and had gained weight normally and undergone vaccination program with no complication unti...

Equine Severe Combined Immunodeficiency

Severe Combined Immunodeficiency (SCID) is a disease with a genetic background in Arabian horses and crossbreeds with Arabians. The disease has been known and documented since the 1970’s and was early suggested to have an autosomal recessive mode of inheritance. Foals that are affected with SCID lack production of both B and T lymphocytes and consequently die from secondary diseases within a sh...

Combined immunodeficiency and thymic abnormalities.

Combined immunodeficiency associated DOCK8 mutations

Results Case report: P.G.O, 9 years old, product of healthy and not consanguinity parents. At age 6 days started a recurrent intestinal bleeding, hypoactivity and fever and was hospitalized with a diagnosis of enterocolitis and sepsis by E.coli. Five days later presented cellulitis and infectious vasculitis in members with decrease of C3. Over the years presented several episodes of pneumonia, ...